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Comment by Susanna C. Larsson

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Epidemiologist and nutrition researcher focused on Mendelian randomization and chronic disease.
Poor diet is a leading cause of morbidity and mortality. However, the causal role of specific foods, nutrients, and other dietary compounds in health and disease is not fully established, as most evidence derives from traditional observational studies. Such studies are susceptible to residual confounding, reverse causation bias, and misclassification of dietary intake.
AI Verified (2022)
Source:
Susanna C. Larsson, special issue information for "Mendelian Randomization Studies on Nutritional Factors and Health Outcomes," Nutrients, 2026.
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Observational nutrition studies are too confounded to show whether eggs cause harm
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AI Verified Relevant: in the source context, the author says conventional observational studies on specific foods do not fully establish causal effects because they are vulnerable to residual confounding, reverse causation, and intake misclassification. Since eggs are a specific food, this gives a clear enough stance signal on the broader claim that observational nutrition studies are too confounded to show whether eggs cause harm. ([mdpi.com](https://www.mdpi.com/journal/nutrients/special_issues/mendelian_randomization_nutritional_health?utm_source=openai)) · YouCongress gpt-5.4-2026-03-05 · 1h ago
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AI Verified The author says the causal role of "specific foods" is "not fully established" because most evidence comes from traditional observational studies that are "susceptible to residual confounding, reverse causation bias, and misclassification of dietary intake." That strongly implies support for the idea that observational nutrition studies are too confounded to determine whether a specific food such as eggs causes harm, even though eggs are not named explicitly. ([mdpi.com](https://www.mdpi.com/journal/nutrients/special_issues/mendelian_randomization_nutritional_health)) · YouCongress gpt-5.4-2026-03-05 · 1h ago

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AI Verified The quote is authentic: the MDPI special-issue URL contains the text verbatim under “Special Issue Information,” and that section is immediately attributed to “Dr. Susanna C. Larsson, Guest Editor.” The same MDPI special-issue page shows a 10 March 2022 submission deadline, and MDPI’s related editorial by Larsson is published in 2022, so the stored year 2022 is consistent. No correction is needed. ([mdpi.com](https://www.mdpi.com/journal/nutrients/special_issues/mendelian_randomization_nutritional_health)) · YouCongress gpt-5.4-2026-03-05 · 1h ago
replying to Susanna C. Larsson