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Comment by French guideline from the French Society of Endocrinology (SFE), the French-speaking Diabetes Society (SFD), the New French-speaking Atherosclerosis Society (NSFA) and the French Society of Cardiology (SFC)

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In hypercholesterolemia, the effect of dietary measures on lowering cholesterol varies from one individual to another and depends on initial LDL-c level. They can reduce total cholesterol and LDL-c levels by 10–15%, or even more in hyper-responders. [...] The impact of dietary cholesterol on serum cholesterol levels is low and varies from one individual to another compared to that of different FAs. Egg yolk is the food richest in cholesterol not associated with FAs.
AI Verified source (2026)
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Policy proposals and claims
Genetic variation (e.g. hyper-responders) makes population-level egg advice misleading for individuals
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Statement relation comments

AI Verified The quote is relevant: it explicitly says cholesterol response to dietary measures and to dietary cholesterol varies across individuals, including 'hyper-responders,' and it discusses eggs specifically. In source context, the same section then gives a population-level recommendation to limit eggs to 7 per week, so the quote is clearly part of the author's reasoning on whether uniform egg advice fits individuals. That makes a stance on the complete statement reasonably determinable, even though the word 'genetic' is only implicit rather than explicit. ([sfdiabete.org](https://www.sfdiabete.org/sites/www.sfdiabete.org/files/files/ressources/management_of_dyslipidemia_in_adults._guidelines_sfe_sfd_nsfa_sfc_2026.pdf)) · YouCongress gpt-5.4-2026-03-05 · 1h ago
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AI Verified The quote acknowledges individual variability (it 'varies from one individual to another' and mentions 'hyper-responders'), but the guideline still concludes that egg studies are inconclusive and that 'it is reasonable to limit egg consumption to 7 per week.' That implies the authors do not see population-level egg advice as misleading for individuals. ([sfdiabete.org](https://www.sfdiabete.org/sites/www.sfdiabete.org/files/files/ressources/management_of_dyslipidemia_in_adults._guidelines_sfe_sfd_nsfa_sfc_2026.pdf)) · YouCongress gpt-5.4-2026-03-05 · 1h ago

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AI Verified The PDF at the provided URL is fetchable and contains the quoted wording verbatim, with the submitter's [...] correctly omitting intervening text. The first sentence appears at page 4, lines 326-329 ("In hypercholesterolemia, the effect of dietary measures on lowering cholesterol... by 10–15%, or even more in hyper-responders."), and the later passage appears at page 4, lines 366-368 ("The impact of dietary cholesterol on serum cholesterol levels is low... Egg yolk is the food richest in cholesterol not associated with FAs."). The same PDF's title matches the named document used as the author, so the attribution is to the document itself, which is acceptable here. The document is a 2026 publication; the stored year is consistent with the source. ([sfdiabete.org](https://www.sfdiabete.org/sites/www.sfdiabete.org/files/files/ressources/management_of_dyslipidemia_in_adults._guidelines_sfe_sfd_nsfa_sfc_2026.pdf)) · YouCongress gpt-5.4-2026-03-05 · 1h ago
replying to French guideline from the French Society of Endocrinology (SFE), the French-speaking Diabetes Society (SFD), the New French-speaking Atherosclerosis Society (NSFA) and the French Society of Cardiology (SFC)