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Comment by Amine Segueni

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Board-certified physician and editor
Roughly 70% of people experience little to no increase in blood cholesterol from dietary sources like eggs. About 30% — often called “hyper-responders” — do show increases in LDL cholesterol. Crucially, these individuals also experience rises in HDL cholesterol and shifts toward larger, less atherogenic LDL particles. This distinction matters because cardiovascular risk is not determined by LDL levels alone.
AI Verified source (Feb 2, 2026)
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Genetic variation (e.g. hyper-responders) makes population-level egg advice misleading for individuals
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AI Verified Relevant: the quote directly addresses person-to-person variation in response to eggs by contrasting the majority with “hyper-responders,” and the source places it in a section on “Individual Response” while criticizing earlier blanket egg/cholesterol messaging as oversimplified and not accounting for human physiology. That makes a determinate stance on whether population-level egg advice can mislead individuals substantially more likely. ([lifeinbalancemd.com](https://lifeinbalancemd.com/eggs-and-cholesterol-myth/)) · YouCongress gpt-5.4-2026-03-05 · 1h ago
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AI Verified The quote supports the statement by emphasizing meaningful individual variation: “70%” have little effect while “30%” are “hyper-responders,” and it adds that “this distinction matters” because risk is not determined by LDL alone. In context, the article’s “Individual Response” section uses this variation to argue against one-size-fits-all egg guidance and toward individualized interpretation. ([lifeinbalancemd.com](https://lifeinbalancemd.com/eggs-and-cholesterol-myth/)) · YouCongress gpt-5.4-2026-03-05 · 1h ago

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AI Verified The exact wording appears verbatim on the source page at lines 46–47, and that same page is bylined to Amine Segueni, MD and dated February 2, 2026, so the submitted quote, attribution, date, and source URL check out. ([lifeinbalancemd.com](https://lifeinbalancemd.com/eggs-and-cholesterol-myth/)) · YouCongress gpt-5.4-2026-03-05 · 1h ago
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