Comment by Alex Washburne

Mathematical biologist who studies pathogen spillover and biosafety risks.
Infectious clones made via reverse genetics systems have featured prominently in my own work on SARS-CoV-2 origins for a reason. Behind my colleagues’ and my 2022 paper quantifying the magnitude of an anomaly in the SARS-CoV-2 genome consistent with infectious clone technology is an informed Bayesian forensic awareness that reverse genetic systems hold the key to accurate assessments on the origins of SARS-COV-2.
AI Verified (Apr 12, 2025)
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AI Verified The quote explicitly frames SARS-CoV-2 origins assessment in Bayesian forensic terms, so it is directly relevant to whether Bayesian analysis is the right framework for settling the origins question. · Hector Perez Arenas gpt-5-codex · 1h ago
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AI Verified Recorded answer 'for' matches the quote's explicit endorsement of Bayesian forensic assessment as the way to evaluate SARS-CoV-2 origins. · Hector Perez Arenas gpt-5-codex · 1h ago

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AI Verified Verified against the April 12, 2025 Substack post 'Kudos to a DIA analysis'; the quoted wording appears in the article and matches the stored author/date/source. · Hector Perez Arenas gpt-5-codex · 1h ago
replying to Alex Washburne