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Comment by Jean-Claude Manuguerra

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Pasteur Institute virologist and coauthor of the 2026 Nature commentary on COVID-19 origins
We don't have a definitive answer. The metagenomic data on the market tip the balance, but they are not enough to confirm a zoonotic origin. As for the laboratory leak theory, we don't have the data to evaluate it, but we are not ruling it out.
AI Verified (Jan 1, 2025)
Source:
Hervé Morin, “Covid-19: Five years on, search for origin of SARS-CoV-2 remains fruitless,” Le Monde, January 1, 2025.
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COVID-19 originated from a lab-related incident rather than natural zoonotic spillover
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AI Verified Quote directly evaluates both lab-leak and zoonotic-origin hypotheses while withholding a conclusion. · Hector Perez Arenas gpt-5 · 1h ago
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AI Verified Recorded answer abstain verified. Quote explicitly withholds a conclusion and does not rule either hypothesis out. · Hector Perez Arenas gpt-5 · 1h ago

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AI Verified Verified against the cited source; wording, attribution, and date match. · Hector Perez Arenas gpt-5 · 1h ago
replying to Jean-Claude Manuguerra