Egg consumption and risk of coronary artery disease, potential amplification by high genetic susceptibility: a prospective cohort study on Genetic variation (e.g. hyper-responder…

Egg consumption and risk of coronary artery disease, potential amplification by high genetic susceptibility: a prospective cohort study

2023 American Journal of Clinical Nutrition study on egg intake, coronary artery disease, and genetic susceptibility.

When stratified by genetic risk, each increment of 3 eggs/wk was associated with a 5% higher risk of CAD for participants at low to intermediate genetic risk (HR: 1.05; 95% CI: 1.01, 1.09), whereas risk increased to HR 1.10 (95% CI: 1.05, 1.16) for those at high genetic risk; a significant synergistic interaction was also indicated at both multiplicative (P interaction = 0.007) and additive (relative excess risk: 0.73; 95% CI: 0.24, 1.22) scales.

AI Verified (Aug 21, 2023)

Source:

"Egg consumption and risk of coronary artery disease, potential amplification by high genetic susceptibility: a prospective cohort study," published online August 21, 2023.

3mo ago

Policy proposals and claims

Genetic variation (e.g. hyper-responders) makes population-level egg advice misleading for individuals

votes For

Statement relation verification history AI Verified Report this

AI Verified Source quote supports a for stance: “When stratified by genetic risk, each increment of 3 eggs/wk was associated with a 5% higher risk of CAD for participants at low to intermediate genetic risk (HR: 1.05; 95% CI: 1.0…” · Hector Perez Arenas gpt-5 · 3mo ago

Vote inference verification history Latest opinion Unverified Report this

No vote answer verification comments yet.

Quote authenticity verification history

Report this

AI Verified The PubMed abstract contains the stored sentence; author corrected from individual coauthors to the study title. · Hector Perez Arenas gpt-5 · 3mo ago

Disputed The quoted sentence appears verbatim in the ScienceDirect abstract of the article, and the paper was published online on August 21, 2023. However, the source lists multiple coauthors (including Ling Yu) rather than attributing the text to Ling Yu alone, so this platform cannot verify it as a single-author Ling Yu quote. ([sciencedirect.com](https://www.sciencedirect.com/science/article/pii/S0002916523659714)) · YouCongress gpt-5.4-2026-03-05 · 3mo ago

replying to Egg consumption and risk of coronary artery disease, potential amplification by high genetic susceptibility: a prospective cohort study

Other opinions from Egg consumption and risk of coronary artery disease, potential amplification by high genetic susceptibility: a prospective cohort study

See all

Egg consumption and risk of coronary artery disease, potential amplification by high genetic susceptibility: a prospective cohort study votes For

Genetic variation (e.g. hyper-responders) makes population-level egg advice misleading for individuals

When the joint effect was examined, in comparison with those at low to intermediate genetic risk and consuming <1 egg/wk, the HR (95% CI) was 2.95 (2.41, 3.62) for participants with high genetic risk and consumption of >=10 eggs/wk, and the correspon...

more Unverified source (Aug 21, 2023)