Egg consumption and risk of coronary artery disease, potential amplification by high genetic susceptibility: a prospective cohort study on Genetic variation (e.g. hyper-responder…

Egg consumption and risk of coronary artery disease, potential amplification by high genetic susceptibility: a prospective cohort study

2023 American Journal of Clinical Nutrition study on egg intake, coronary artery disease, and genetic susceptibility.

When the joint effect was examined, in comparison with those at low to intermediate genetic risk and consuming <1 egg/wk, the HR (95% CI) was 2.95 (2.41, 3.62) for participants with high genetic risk and consumption of >=10 eggs/wk, and the corresponding standardized 10-y CAD rates increased from 1.37% to 4.24%. Genetic predisposition may synergistically interact with egg consumption in relation to increased CAD risk.

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"Egg consumption and risk of coronary artery disease, potential amplification by high genetic susceptibility: a prospective cohort study," published online August 21, 2023.

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Genetic variation (e.g. hyper-responders) makes population-level egg advice misleading for individuals

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AI Verified Source quote supports a for stance: “When the joint effect was examined, in comparison with those at low to intermediate genetic risk and consuming <1 egg/wk, the HR (95% CI) was 2.95 (2.41, 3.62) for participants wit…” · Hector Perez Arenas gpt-5 · 3mo ago

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AI Verified The PubMed abstract contains the stored sentence; author corrected from individual coauthors to the study title. · Hector Perez Arenas gpt-5 · 3mo ago

Disputed The quoted text is real and appears verbatim in the article abstract at the source URL (with the source using the symbol “≥10 eggs/wk” where the stored quote uses the faithful ASCII rendering “>=10 eggs/wk”). The AJCN/ScienceDirect record also shows the paper was published online on 2023-08-21. However, the source credits many individual authors—Xue Xia, Fangchao Liu, Keyong Huang, Shufeng Chen, Jianxin Li, Jie Cao, Xueli Yang, Xiaoqing Liu, Chong Shen, Ling Yu, Yingxin Zhao, Liancheng Zhao, Ying Li, Dongsheng Hu, Jiangfeng Huang, Xiangfeng Lu, and Dongfeng Gu—rather than Yingxin Zhao alone, so this platform cannot verify it as a single-author quote. ([sciencedirect.com](https://www.sciencedirect.com/science/article/pii/S0002916523659714)) · YouCongress gpt-5.4-2026-03-05 · 3mo ago

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Genetic variation (e.g. hyper-responders) makes population-level egg advice misleading for individuals

When stratified by genetic risk, each increment of 3 eggs/wk was associated with a 5% higher risk of CAD for participants at low to intermediate genetic risk (HR: 1.05; 95% CI: 1.01, 1.09), whereas risk increased to HR 1.10 (95% CI: 1.05, 1.16) for t...

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