Comment by Bernard Rosner

In Asian cultures, eggs are typically incorporated into various cuisines, while in Western populations, eggs are typically consumed with red and processed meats and refined grains. Additionally even though analyses of the China Kadoorie Biobank were adjusted for household income and education level, the inverse association could reflect a social gradient. [...] Thus, data from the China Kadoorie Biobank study are probably affected by residual confounding related to egg consumption patterns and socioeconomic status.